Intended for healthcare professionals


Fatal methadone overdose

BMJ 1996; 313 doi: (Published 07 December 1996) Cite this as: BMJ 1996;313:1479

Better understanding of body's handling of methadone is needed

  1. Emyr W Benbow,
  2. Ian S D Roberts,
  3. Alison Cairns
  1. Senior lecturer in pathology Lecturer in pathology University of Manchester, Manchester M13 9PT
  2. Registrar in pathology Leeds General infirmary, Leeds LS1 3EX

    EDITOR,—T J Hendra and colleagues describe a case in which postmortem concentrations of methadone were substantially higher than those in a sample of blood taken, by our calculations, about 28 hours before death.1 They speculate that this indicates either delayed absorption from the gut or surreptitious consumption of methadone after admission to hospital. We suggest …

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