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Paracetamol-codeine combinations versus paracetamol alone

BMJ 1996; 313 doi: (Published 09 November 1996) Cite this as: BMJ 1996;313:1209
  1. A Li Wan Po,
  2. W Y Zhang
  1. Professor of clinical pharmaceutics Research fellow Centre for Evidence Based Pharmacotherapy, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD

    EDITOR,—In their systematic review Anton J M de Craen and colleagues conclude, on the basis of a range of outcome measures, that the combination of paracetamol and codeine is a more effective analgesic than paracetamol alone.1 They find the increase in efficacy to be small but significant and suggest that future studies should report the proportion of patients in whom good or …

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