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Patients who have had fractures of the distal forearm do not lose bone as expected

BMJ 1996; 313 doi: (Published 28 September 1996) Cite this as: BMJ 1996;313:821
  1. R W Keen, Clinical research fellow,
  2. G O Griffiths, Statistician,
  3. T D Spector, Consultant rheumatologist
  1. Twin Research and Osteoporosis Unit, St Thomas's Hospital, London SE1 7EH

    EDITOR,—Women's lifetime risk of experiencing a fracture of the distal forearm is 15%.1 Such fractures are associated with considerable pain and morbidity. They are also associated with an increased risk of vertebral fracture,2 although these anatomical sites have different bone compositions, with the forearm being composed predominantly of cortical bone whereas the spine is composed predominantly of trabecular bone.

    In response to the work by N F A Peel and colleagues3 we have prospectively examined rates of bone loss at the lumbar spine over …

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