Medicine And Books

Variation in the Human Genome

BMJ 1996; 313 doi: (Published 17 August 1996) Cite this as: BMJ 1996;313:433
  1. Ian D Young

    Ed Derek Chadwick, Gail Cardew Wiley, £52.50, pp 329 ISBN 0 471 96152 3

    It will not come as a surprise to doctors that the human genome has been shown to be a complex and diverse entity. Patients show striking and sometimes idiosyncratic differences in their responses to noxious agents and to treatment. If these differences exist today then plausibly they existed in the past, and perhaps this explains why some of our ancestors were able to survive the horrors of famine and plague while others around them succumbed. The underlying explanations for these events must surely lie in our extraordinarily rich and heterogeneous genetic heritage.

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