Laboratories should use serum IgM tests to confirm measles

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7036.975c (Published 13 April 1996) Cite this as: BMJ 1996;312:975
  1. Laura Ryall,
  2. Colin Goodbourn,
  3. Anne Taylor,
  4. Louise Teare
  1. Senior medical laboratory scientific officer (virology) Registrar Medical laboratory scientific officer (virology) Director Chelmsford Public Health Laboratory, Chelmsford, Essex CM2 0YX

    EDITOR,—We agree with Dereck R Tait and colleagues about the importance of laboratory confirmation of exanthems for surveillance purposes.1 The salivary IgM assay has been used successfully during the recent measles and rubella vaccination campaign in selected districts2 but is not yet available commercially. Serum measles IgM assays are now available, although in our experience the complement fixation test is still used widely for screening. A comparison of the methods has led us to believe that many cases of measles …

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