Authors' reply

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7033.778b (Published 23 March 1996) Cite this as: BMJ 1996;312:778
  1. M Impallomeni,
  2. J Starr,
  3. T Rogers
  1. Consultant Senior registrar Care of the Elderly Unit, Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London W12 0NN
  2. Professor Department of Infectious Diseases, Royal Postgraduate Medical School

    EDITOR,—Eugene Rothschild and colleagues question the validity of our conclusion that the recent outbreak of diarrhoea due to Clostridium difficile in our wards was attributable to the 20-fold increase in consumption of cefotaxime. This increase occurred after the British Thoracic Society published guidelines on the treatment of severe community acquired pneumonia. However, all other risk factors in our patients had apparently remained unchanged. Rothschild and colleagues doubt the soundness of using “notional courses” to quantify antibiotic …

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