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BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7033.777a (Published 23 March 1996) Cite this as: BMJ 1996;312:777
  1. Elizabeth Barrett-Connor,
  2. Deborah Goodman-Gruen
  1. Professor Medical fellow Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093-0607, USA

    EDITOR,—Paola Muti and Maurizio Trevisan are concerned that the absence of any association between oestrogen concentration and the risk of fatal cardiovascular disease in our study may have been due to dissociation of bioavailable oestrogen in the frozen samples over time. The papers they cite raise the possibility of dissociation but do …

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