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Plasma cholesterol response to dietary saturated fat

BMJ 1996; 312 doi: (Published 24 February 1996) Cite this as: BMJ 1996;312:511

Conclusions are based on circular arguments

  1. Susanne Doepfmer,
  2. Irene Guggenmoos-Holzmann
  1. Research assistant Professor of medical statistics Department of Medical Statistics, Free University Berlin, 12200 Berlin, Germany

    EDITOR,—Charlotte Cox and colleagues report a double crossover trial looking at individual variation in the response of plasma cholesterol concentrations to dietary saturated fat.1 Responsiveness to diet was calculated for each subject as the difference between total cholesterol concentration during two types of diet. Consistent responders were then defined as those in whom the difference between the two differences …

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