Authors' reply

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7029.510a (Published 24 February 1996) Cite this as: BMJ 1996;312:510
  1. D J P Barker,
  2. C Osmond,
  3. I Rodin,
  4. C H D Fall,
  5. P D Winter
  1. Director Statistician Registrar Epidemiologist Computing manager MRC Environmental Epidemiology Unit, Southampton General Hospital, Southampton SO16 6YD

    EDITOR,—Chris Hollis is incorrect in several respects. To suggest that prenatal programming of key endocrine axes is linked to later disease is not deterministic.1 Persisting changes in endocrine function arising in utero do not necessarily affect …

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