Figures on screening for Down's syndrome are inaccurate

BMJ 1996; 312 doi: https://doi.org/10.1136/bmj.312.7027.379a (Published 10 February 1996) Cite this as: BMJ 1996;312:379
  1. Anne Kennard,
  2. Eva Alberman,
  3. Mike Gill
  1. Lecturer Professor Wolfson Institute of Preventive Medicine, Medical College of St Bartholomew's Hospital, London EC1M 6BQ
  2. Director of public health Brent and Harrow Health Authority, Harrow, Middlesex HA1 3EX

    EDITOR,—Philip Steer's comments about serum screening for Down's syndrome1 should not go unchallenged. Firstly, it is inappropriate to cite a 48% detection rate. For a 5% false positive rate the estimated detection rate is 59% when dates are used to estimate gestational age and 65% if an estimate based on an ultrasound scan is used.2 …

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