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BMJ 1995; 311 doi: (Published 08 July 1995) Cite this as: BMJ 1995;311:138

Further evidence refuting an association between silicone breast implants and connective tissue disorders comes from the US nurses health study (New England Journal of Medicine 1995;322:1666-70). Among the 87 501 women followed up, 516 developed connective tissue disorders and 1183 had breast implants. The relative risk of connective tissue disease among those with silicone implants was 0.3 (95% confidence interval 0 to 1.9).

How strong is the evidence for routine use of dexamethasone in patients with acute bacterial meningitis? Not strong enough, say the authors of a review article in the “Journal of Neurology, Neurosurgery and Psychiatry” (1995;59:31-7), which concludes that none of the studies published so far has adhered to all the methodological principles of a sound controlled clinical trial. A depressingly familiar story.

Six further cases of Ebola haemorrhagic fever have been reported in Kikwit in Zaire since 6 June, although fortunately these are not thought to represent new foci of the disease (WHO Weekly Epidemiological Record 1995;24:176). This brings the total number of cases to 282. Among patients whose outcome is known, 80% have died.

And more worrying news about a viral outbreak comes from Australia. The “Medical Journal of Australia” (1995;162:621) …

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