Antidepressants and suicide

BMJ 1995; 311 doi: https://doi.org/10.1136/bmj.311.6996.55 (Published 01 July 1995) Cite this as: BMJ 1995;311:55
  1. Ian Whyte,
  2. Nick Buckley,
  3. Greg Carter
  1. Senior staff specialist Senior lecturer Senior staff specialist Department of Clinical Toxicology and Pharmacology, Hunter Area Health Service, Newcastle Mater Misericordiae Hospital, Locked Bag 7, Hunter Regional Mail Centre, NSW 2310, Australia

    Study analyses were flawed

    EDITOR,--Two recent articles look at use of antidepressants and death from suicide. John A Henry and colleagues have continued previous work and assessed the relation between death and defined daily dose.1 Unfortunately, the defined daily dose for dothiepin used in the paper (75 mg) should be 150 mg (references quoted by Henry and colleagues). The correct figure is then 3.08 deaths per million defined daily doses of dothiepin instead of 1.54--the second highest figure, after that for amoxapine. This agrees with a clinical study that …

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