Treating heart disease

BMJ 1995; 310 doi: https://doi.org/10.1136/bmj.310.6992.1470a (Published 03 June 1995) Cite this as: BMJ 1995;310:1470

Estimate of benefit from early thrombolysis in acute myocardial infarction is wrong

  1. John Rawles
  1. Honorary senior lecturer in medicine Medicines Assessment Research Unit, University of Aberdeen, Aberdeen AB9 2ZD

    EDITOR,—Anthony Hall and D M Humphreys from Boehringer Ingelheim1 are not alone in uncritically accepting the estimate of the benefit conferred by earlier thrombolysis produced by the Fibrinolytic Therapy Trialists' Collaborative Group.2 Within five weeks of entry to the trial the loss of benefit per hour of delay to randomisation is given as 1.6/1000 patients. This figure is so low that, if it is true, many would feel that the effort required to expedite thrombolysis, particularly to take it out of hospital into the community, …

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