Assessing blood glucose control in diabetes mellitus

BMJ 1995; 310 doi: https://doi.org/10.1136/bmj.310.6981.740a (Published 18 March 1995) Cite this as: BMJ 1995;310:740

Use precise analytical methods

  1. Susan Standing,
  2. Richard Taylor
  1. Clinical biochemist Clinical biochemist Department of Clinical Biochemistry, John Radcliffe Hospital, Oxford OX3 9DU

    EDITOR,—In their study of the use of glycated haemoglobin concentrations to indicate glycaemic control Eric S Kilpatrick and colleagues used targets, related to the methods used, which were based on multiples of the SD of a reference range derived from non-diabetic subjects.1 They found considerable differences in the classification of diabetic patients, which depended on the method, despite the methods giving similar absolute values for haemoglobin A1(HbA1).2 This, however, does not necessarily show different measurements of glycated haemoglobin to be inherently non-comparable indicators of …

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