Authors' reply

BMJ 1995; 310 doi: https://doi.org/10.1136/bmj.310.6975.328 (Published 04 February 1995) Cite this as: BMJ 1995;310:328
  1. Philip S Rice,
  2. Jangu E Banatvala,
  3. Robert Carr,
  4. Katy Simmons
  1. Senior registrar in virology Guy's and St Thomas's Hospital Trust, St Thomas's Hospital, London SE1 7EH
  2. Professor of clinical virology Senior lecturer in haematology Lecturer in haematology United Medical and Dental Schools of Guy's and St Thomas's Hospitals, St Thomas's Campus, London SE1 7EH

    EDITOR,—Paul Buss and Isobel Burnett express concern about our recommendation that varicella-zoster immunoglobulin should be given to non-immune patients exposed to chickenpox who have received systemic steroids within the previous three months, a recommendation made by the Committee on Safety of Medicines earlier last year.1 Depression of cell mediated immune responses occurs within four to six hours of administration of steroids. Therefore a short course of steroids given within the incubation period of chickenpox might impair host responses.2 Even if short courses …

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