Circadian variation in deliberate self poisoning

BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6968.1583d (Published 10 December 1994) Cite this as: BMJ 1994;309:1583
  1. Jonathan R Price
  1. Senior house officer in rheumatology, rehabilitation, and metabolic medicine Nuffield Orthopaedic Centre, Oxford OX3 7LD.

    EDITOR,—Roberto Manfredini and colleagues present data showing circadian variation in the incidence of deliberate self poisoning as determined by assessment of admissions to an Italian accident and emergency department.1 I am concerned, however, by their conclusion that “treatment of depressive disorders might therefore be improved by aiming for peak drug concentrations at vulnerable times.”

    A large proportion of their patients would not have been …

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