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Transmission of tuberculosis by patients with HIV infection

BMJ 1994; 309 doi: (Published 03 December 1994) Cite this as: BMJ 1994;309:1515
  1. G M Scott,
  2. J Holton
  1. Infection control doctor, Infection control doctor, Clinical Microbiology, University College London Hospitals, London WC1E 6AU.

    EDITOR,—R J Kent and colleagues used restriction fragment length polymorphism analysis to show that three strains of Mycobacterium tuberculosis from patients positive for HIV at this hospital were indistinguishable.1 The results became available to us only one year later. Our investigation could not identify a plausible route of transmission.

    Case 1—The index patient (a 25 year old South American man) was on a ward remote from the AIDS unit between 15 and 25 June. He had fever, a dry cough, weight loss, and shadowing of the right middle lobe but with neutropenia and lymphopenia and antibodies to HIV. He was transferred on 25 June to a side room on AIDS ward A …

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