Reye's syndrome

BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6966.1443a (Published 26 November 1994) Cite this as: BMJ 1994;309:1443
  1. Maria Casteels-Van Daele,
  2. Ephrem Eggermont
  1. Professor of general paediatrics Professor of paediatrics, Department of Paediatrics, University Hospital Gasthuisberg, University of Leuven, 3000 Leuven, Belgium.

    EDITOR,—Susan M Hall has commented1 on our statement that Reye's syndrome should be reassessed.2 As we originally emphasised, the fact that Reye's syndrome is a heterogeneous condition implies that the North American and British epidemiological studies were done on a heterogeneous group of children with quite different—viral, metabolic, or toxic—diseases. This compromises the data suggesting a link between Reye's syndrome and aspirin, as the definition of a “case subject” must be specific for …

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