BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6960.1028 (Published 15 October 1994) Cite this as: BMJ 1994;309:1028
  1. J P Fisher

    Research workers in Sweden have shown that full thickness defects in the articular cartilage of the knee may be repaired by transplantation of cultured chondrocytes (New England Journal of Medicine 1994;331:889-95). The chondrocytes were removed from the knees at arthroscopy, cultured for 14-21 days, and then injected into the defect and covered with a flap of periosteum. Two years after transplantation 14 of 16 patients with lesions of their femoral condyles had good to excellent results; the outcome was less encouraging in seven patients with patellar lesions, only two of whom had good results.

    The belief that mercury poisoning makes the teeth fall out is probably a hangover from the days when mercury compounds were given in high doses as part of the treatment of syphilis. A study from Norway reported in “Occupational and Environmental Medicine” (1994;51:656-9) looked at the health of workers exposed to mercury vapour at a chloralkali plant. No evidence was found of any dental problems in these workers: they had as many teeth as controls, and their teeth were in similar condition.

    The race for the identification of the precise location of the breast cancer gene has been won by …

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