Value of Kleihauer test

BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6960.1020d (Published 15 October 1994) Cite this as: BMJ 1994;309:1020
  1. R P Balfour,
  2. F G Williams,
  3. J A F Napier
  1. Princess of Wales Hospital, Bridgend, Mid Glamorgan CF31 1RQ National Blood Transfusion Service (Wales), Rhydlafar, Cardiff

    EDITOR, - Jennifer K M Duguid and Imelda Bromilow question the reliability of the Kleihauer test,1 while Elizabeth A Letsky and Mahes de Silva suggest that a higher dose of anti-D immunoglobulin would eliminate use of the test.2 We report a case showing the danger of this proposal.

    A woman who was group O RhD negative delivered a baby who was group O RhD positive in 1989 and was given the standard dose of 500 IU of anti-D immunoglobulin. In her second pregnancy in 1992 screening for antibodies …

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