Antidepressants and suicide

BMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6943.1573a (Published 11 June 1994) Cite this as: BMJ 1994;308:1573
  1. E Vuori,
  2. J Lonnqvist,
  3. T Klaukka
  1. University of Helsinki, Department of Forensic Medicine, PO Box 40 (Kytosuontie 11), FIN 00014
  2. University of Helsinki, Finland National Public Health Institute, Department of Mental Health, FIN 00300
  3. Helsinki Social Insurance Institution of Finland, PO Box 78, FIN 00381 Helsinki.

    EDITOR, - Goran Isacsson and colleagues examined the use of various antidepressants among people who committed suicide and concluded that therapeutic failure may be a greater problem than toxicity.1 They state that they refrained from ranking different drugs, but this occurred in practice because the differences found were explained on the grounds of the weaker antidepressive effect of the newer drugs, moclobemide and mianserin. The basis for the authors' conclusion was that, despite their relatively low toxicity, both drugs were overrepresented in the people who had committed suicide compared with their use in general.

    The rate of suicide in Finland …

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