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Fluoroquinolones in chronic obstructive pulmonary disease

BMJ 1994; 308 doi: (Published 28 May 1994) Cite this as: BMJ 1994;308:1437
  1. A Colville,
  2. M Knowles,
  3. D Large,
  4. J George,
  5. P Mustchin
  1. Carlisle Public Health Laboratory, Cumberland Infirmary, Carlisle CA2 7HY Cumberland Infirmary, Carlisle CA2 7HY.

    EDITOR, - In their editorial Harold Hosker and colleagues suggest that fluoroquinolones are suitable second line antibiotics for infective exacerbations of chronic obstructive pulmonary disease.1 We report two cases that illustrate our reservations about this suggestion.

    Case 1 - A 75 year old woman was admitted complaining of severe shortness of breath and right sided pleuritic chest pain. She had been admitted several times before with exacerbation of chronic obstructive pulmonary disease. Before this admission she had taken ciprofloxacin 500 mg twice daily and prednisolone for six …

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