Hannah's Heirs: The Quest for the Genetic Origins of Alzheimer's DiseaseBMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6937.1176 (Published 30 April 1994) Cite this as: BMJ 1994;308:1176
- Theresa Marteau
Daniel A Pollen Oxford University Press, pounds sterling 16.95, pp 296 ISBN 0-19-506809-2
During a six week period in the autumn of 1992, three research groups independently published their discovery of the link between the abnormal gene for familial Alzheimer's disease and the long arm of chromosome 14. Daniel Pollen, a neurologist, tells his story of this discovery, starting with a visit to his surgery, seven years earlier, of a member of one of the largest known families affected by familial Alzheimer's disease.
The personal tragedy of Jeff's diagnosis was tempered by the pedigree that he had brought with him. The family was documented back to the birth of …