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Risk factors for salmonella infection: Loss of gastric acid linked to candidiasis

BMJ 1994; 308 doi: (Published 26 February 1994) Cite this as: BMJ 1994;308:596
  1. A J Larner
  1. Department of Anatomy, University of Cambridge, Cambridge CB2 3DY
  2. University of Health Sciences, Chicago Medical School, North Chicago, IL 60064-3095, USA.

    EDITOR, - Keith R Neal and colleagues report that recent treatment with H2 antagonists and gastric surgery predispose to salmonella infection, presumably as a result of reduced production of gastric acid.1 A protective effect of gastric acid against the non-typhoid salmonelloses has been suspected.2 Another potential infective complication of reduced secretion of gastric acid is candidiasis.

    There have been anecdotal reports of both local and systemic candidal infections after various interventions that produce …

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