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Renal failure after topical use of NSAIDs

BMJ 1994; 308 doi: (Published 19 February 1994) Cite this as: BMJ 1994;308:533
  1. A H N Fernando,
  2. R M Temple,
  3. S Thomas,
  4. H A Lee
  1. Wessex Renal and Transplant Unit, St Mary's Hospital, Portsmouth PO3 6AD.

    EDITOR, - We wish to amplify the case reports of C A O' Callaghan and colleagues1 by reporting on a patient who developed acute renal failure twice: once after taking ibuprofen orally and once after topical administration of the drug.

    A 76 year old man was admitted with acute anuric renal failure five days after taking four tablets of ibuprofen for a muscle strain. In the 48 …

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