Osteoporotic fractures Target whole population for prevention

BMJ 1994; 308 doi: https://doi.org/10.1136/bmj.308.6923.274b (Published 22 January 1994) Cite this as: BMJ 1994;308:274
  1. M H Duncan
  1. Charing Cross Hospital, London W6 8RF.

    EDITOR, - Tuan Nguyen and colleagues combined measurements of bone mineral density, muscle strength, and postural stability to predict osteoporotic fractures.1 This outperforms many previous protocols, but their use of discriminant function analysis to derive sensitivity figures in excess of 80% is both unusual and potentially misleading. The term sensitivity should have been reserved for the proportion of people subsequently sustaining fractures who had had a positive test result (in this case a combination of poor results for bone mineral density, muscle …

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