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Hyposplenic patients need prophylactic penicillin

BMJ 1994; 308 doi: (Published 08 January 1994) Cite this as: BMJ 1994;308:132
  1. A F Muller,
  2. P J Toghill
  1. City Hospital, Nottingham NG5 1PB University Hospital, Queen's Medical Centre, Nottingham NG7 2UH.

    EDITOR,- We welcome the articles highlighting the risk of serious infection in patients who have had a splenectomy,*RF 1-3* but this may be only part of the problem: old age and several disparate diseases are associated with hyposplenism in people with an intact spleen. Functional hyposplenism of this kind also renders patients vulnerable …

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