Research Article

Diarrhoeae in thyroid medullary carcinoma: role of prostaglandins and therapeutic effect of nutmeg.

Br Med J 1975; 3 doi: (Published 05 July 1975) Cite this as: Br Med J 1975;3:11
  1. J A Barrowman,
  2. A Bennett,
  3. P Hillenbrand,
  4. K Rolles,
  5. D J Pollock,
  6. J T Wright


    In a patient with medullary carcinoma of the thyroid with pulmonary metastases who presented with diarrhoea and steatorrhoea large amounts of prostaglandin-like material were present in peripheral blood, and some was extracted from the tumour. The diarrhoea which persisted after thyroidectomy responded to treatment with nutmeg.