Papers And Originals

Simplified Method for Determining Acetylator Phenotype

Br Med J 1972; 3 doi: (Published 26 August 1972) Cite this as: Br Med J 1972;3:506
  1. Hasse Schröder


    A chemical method has been developed for estimating the acetylator phenotype without the use of special equipment. One urine specimen taken after ingestion of sulphadimidine, sulphapyridine, or sulphasalazine is required. The acetylator phenotype was assessed correctly in 150 urine specimens from 100 healthy subjects. Between 15 and 25 specimens can be determined hourly. Urine specimens for the test can be stored for two weeks at 37°C without any loss of drugs or their metabolites.