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Rhesus Isoimmunization after Abortion

Br Med J 1971; 3 doi: (Published 10 July 1971) Cite this as: Br Med J 1971;3:90
  1. Sheilagh Murray,
  2. S. L. Barron


    Out of 177 Rh(D)-negative patients studied, 96 were successfully followed-up after spontaneous or therapeutic abortion. Rh antibodies were detected by the indirect Coombs test in two patients and by an enzyme technique only in a further seven, an overall incidence of 9·4%.

    The prophylactic use of anti-D immunoglobulin is now recommended for Rh-negative non-immunized patients undergoing abortion, but the dose could be less than 75 μg. The Kleihauer test was of no value in predicting the risk of isoimmunization.