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Papers And Originals

Betamethasone 17-Valerate and Prednisolone 21-Phosphate Retention Enemata in Proctocolitis: A MULTICENTRE TRIAL

Br Med J 1971; 3 doi: https://doi.org/10.1136/bmj.3.5766.84 (Published 10 July 1971) Cite this as: Br Med J 1971;3:84

Abstract

The efficacy of betamethasone 17-valerate (5 mg) and prednisolone 21-phosphate (20 mg) retention enemata in the outpatient treatment of distal proctocolitis was compared in a formal clinical trial. The two treatments were equally effective in inducing remissions of the disease, but the betamethasone valerate enema produced less adrenal suppression.