Preliminary Communications

Free Amino-acid Concentrations in Fetal Fluids

Br Med J 1970; 3 doi: (Published 26 September 1970) Cite this as: Br Med J 1970;3:747

This article has a correction. Please see:

  1. F. Cockburn,
  2. S. P. Robins,
  3. J. O. Forfar


    The pattern of free amino-acid concentrations in maternal venous plasma, fetal umbilical arterial plasma, fetal urine, and amniotic fluid at 15 to 20 weeks' gestation has been determined. Free amino-acid concentrations were greater in fetal plasma than in maternal plasma, amniotic fluid, or fetal urine.

    The ratios of amino-acid concentrations in fetal umbilical arterial plasma and urine indicate that the fetal kidney can effectively conserve amino-acids, possibly reaching an adult level of competence in this respect.

    There was little correlation between amino-acid concentrations in the fluids analysed with the exception of that between amniotic fluid and fetal urine.

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