Development of Vascular Lesions in Insulin-treated Animals Fed a Normal DietBr Med J 1970; 3 doi: https://doi.org/10.1136/bmj.3.5724.685 (Published 19 September 1970) Cite this as: Br Med J 1970;3:685
- R. W. Stout
Experiments were undertaken to study the role of hyperinsulinism in the pathogenesis of atheroma. Chickens injected with long-acting insulin for 19 weeks developed lipid containing lesions in their aortas. This provides further evidence in favour of the hypothesis that insulin and atheroma are causally related.