Preliminary Communications

Glycolytic Enzymes in Adipose Tissue of Adult Diabetics

Br Med J 1970; 3 doi: (Published 22 August 1970) Cite this as: Br Med J 1970;3:444
  1. D. J. Galton,
  2. J. P. D. Wilson


    The maximal activities of hexokinase and phosphofructokinase were measured in human adipose tissue. Though the mean activity of hexokinase was similar between a group of adult diabetics (n=24) and a group of non-diabetic controls (n=25), in the diabetic group the activity of phosphofructokinase was definitely reduced. Possibly this enzyme deficiency might contribute to impaired glucose utilization by the adipose cell in diabetes.

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