Preliminary Communications

Urographic Changes in Acute Papillary Necrosis in the Rat

Br Med J 1970; 3 doi: (Published 01 August 1970) Cite this as: Br Med J 1970;3:263
  1. R. A. Risdon,
  2. C. L. Berry,
  3. A. R. Chrispin


    Intravenous high-dosage urography was performed in rats which had renal papillary necrosis induced with ethyleneimine or renal tubular necrosis produced with mercuric chloride. In both groups, nephrograms were abnormally persistent. In animals treated with ethyleneimine dense selective opacification of the necrotic renal pyramid occurred. It is suggested that this selective opacification may be a valuable radiological sign of recent renal papillary necrosis.

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