Papers And Originals

Scleroderma and Primary Biliary Cirrhosis

Br Med J 1970; 3 doi: (Published 01 August 1970) Cite this as: Br Med J 1970;3:258
  1. I. M. Murray-Lyon,
  2. R. P. H. Thompson,
  3. I. D. Ansell,
  4. Roger Williams


    Two cases of scleroderma and primary biliary cirrhosis are described. One had systemic sclerosis with primary biliary cirrhosis of six years' duration at the stage of ductular proliferation. The other had the C.R.S.T. syndrome (calcinosis, Raynaud's phenomenon, sclerodactyly, and telangiectases) with primary biliary cirrhosis at the florid stage. Several similar cases were found in a review of other reports, and it is suggested that the association may be due to a common “autoimmune” process.