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Severe Depressive Mood Changes Following Slow-release Intramuscular Fluphenazine Injection

Br Med J 1969; 3 doi: (Published 06 September 1969) Cite this as: Br Med J 1969;3:564
  1. R. de Alarcon,
  2. M. W. P. Carney


    Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection. In five cases this depression is thought to have been responsible for suicide. In 8 out of 10 cases the depression responded to electroplexy (E.C.T.). It is recommended that patients who are treated with fluphenazine should be carefully supervised.