Papers And Originals

Clinical Evaluation of Adriamycin, a New Antitumour Antibiotic

Br Med J 1969; 3 doi: (Published 30 August 1969) Cite this as: Br Med J 1969;3:503
  1. Gianni Bonadonna,
  2. Silvio Monfardini,
  3. Mario de Lena,
  4. Franca Fossati-Bellani


    Adriamycin, a new antitumour antibiotic of the anthracycline group with a structural formula very similar to daunorubicin, has proved to have potent tumour-growth-inhibiting properties, and to be particularly effective in childhood malignancies. Though adriamycin produces a higher percentage of side-effects than daunorubicin—namely, stomatitis and alopecia—a lower dosage may be used for therapy.