Intended for healthcare professionals

Research Article

Impotence: treatment by autoinjection of vasoactive drugs.

Br Med J (Clin Res Ed) 1987; 295 doi: (Published 05 September 1987) Cite this as: Br Med J (Clin Res Ed) 1987;295:595
  1. G Williams,
  2. M J Mulcahy,
  3. E A Kiely
  1. Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London.


    One hundred and twenty five men with psychogenic or organic impotence used autoinjection of the penile corpora cavernosa with either papaverine or papaverine and phentolamine for a mean period of 10.5 months (range 1-24 months) to achieve penile erection for sexual intercourse. Prolonged (over four hours) painless erection resulted from 34 of the 3513 self administered injections. This seems to be a highly effective approach to treating impotence irrespective of the aetiology.