Intended for healthcare professionals

Research Article

Reproduction of epigastric pain of duodenal ulceration by adenosine.

Br Med J (Clin Res Ed) 1987; 294 doi: (Published 03 January 1987) Cite this as: Br Med J (Clin Res Ed) 1987;294:10
  1. A H Watt,
  2. D J Lewis,
  3. J J Horne,
  4. P M Smith


    Intravenous boluses of adenosine produced transient epigastric discomfort indistinguishable from spontaneous pain in five of six patients with endoscopically confirmed duodenal ulcer, an effect which was slightly but significantly antagonised by aminophylline. These findings may be relevant to the pathophysiology of peptic ulcer pain.