Intended for healthcare professionals

Research Article

Prevalence of antibody to poliovirus in England and Wales 1984-6.

Br Med J (Clin Res Ed) 1986; 293 doi: (Published 01 November 1986) Cite this as: Br Med J (Clin Res Ed) 1986;293:1153
  1. P M White,
  2. J Green


    Serum from 995 subjects aged 6 months to 99 years was screened at a dilution of 1/8 for neutralising antibodies to poliovirus. Of these samples, 975 (98%) contained antibody to at least one serotype, and 763 (77%) contained antibody to all three, an improvement since previous studies. Children aged 8 to 15, however, had a low prevalence of antibody to poliovirus type 3, with only four (40%) of those aged 12 protected. This finding is possibly due to the waning of antibodies induced by the type 3 component of oral poliovirus vaccine and emphasises the continued importance of a booster dose of vaccine for those leaving school.