Research Article
Subcutaneous terbutaline and control of brittle asthma or appreciable morning dipping.
Br Med J (Clin Res Ed) 1984; 288 doi: https://doi.org/10.1136/bmj.288.6432.1715 (Published 09 June 1984) Cite this as: Br Med J (Clin Res Ed) 1984;288:1715
- J Ayres,
- D R Fish,
- D C Wheeler,
- J Wiggins,
- G M Cochrane,
- C Skinner
Abstract
In a pilot study two patients with brittle asthma and two with morning dipping received terbutaline or a placebo administered subcutaneously either by continuous infusion or in injections every six hours. In two patients brittle asthma was completely suppressed by terbutaline 1 mg/day given by either method. In the two others early morning dipping responded only to continuous subcutaneous infusions of terbutaline 12 mg/day. Terbutaline administered subcutaneously may be an effective treatment in asthmatic patients who show important diurnal variations in air flow.