Research Article

Clinicopathological observations on metastasis in man studied in patients treated with peritoneovenous shunts.

Br Med J (Clin Res Ed) 1984; 288 doi: (Published 10 March 1984) Cite this as: Br Med J (Clin Res Ed) 1984;288:749
  1. D Tarin,
  2. J E Price,
  3. M G Kettlewell,
  4. R G Souter,
  5. A C Vass,
  6. B Crossley


    Fourteen patients with inoperable cancer treated with peritoneovenous shunts for malignant ascites were studied post mortem. Clinical observations and findings at necropsy indicated that peritoneovenous shunting does not result in the establishment of clinically important haematogenous metastases and that metastases do not necessarily develop even when large numbers of viable tumour cells regularly enter the blood. Peritoneovenous shunting provides a unique opportunity for collecting data on the spread of tumours in man.