Intended for healthcare professionals

Research Article

Severe diabetic microangiopathy with normal glucose tolerance and pituitary infarction.

Br Med J (Clin Res Ed) 1983; 287 doi: (Published 22 October 1983) Cite this as: Br Med J (Clin Res Ed) 1983;287:1168
  1. R W Bilous,
  2. R N Poston,
  3. H Keen,
  4. G C Viberti


    Blood glucose concentrations in a woman with severe retinopathy, nephropathy, and neuropathy were found to be within the normal range. A high random blood glucose concentration was recorded only once, six months before her initial presentation. At necropsy the anterior lobe of the pituitary gland showed old, extensive infarction. Occult pituitary hypofunction may explain severe diabetic microangiopathy in patients with normal glucose tolerance.