Research Article

Lacunar infarcts in polycythaemia with raised packed cell volumes.

Br Med J (Clin Res Ed) 1983; 287 doi: (Published 01 October 1983) Cite this as: Br Med J (Clin Res Ed) 1983;287:935
  1. J M Pearce,
  2. C P Chandrasekera,
  3. E J Ladusans


    Lacunar (small deep cerebral infarcts) infarction is described in association with raised packed cell volumes. Two patients had polycythaemia vera, one stress polycythaemia. They presented with transient ischaemic episodes and were shown by computed tomography to have lacunes deep in the basal ganglia and internal capsule. Such lesions may be caused by small vessel occlusions related to increased viscosity and impaired oxygen consumption by adjacent tissues. Finding a raised packed cell volume in patients with lacunes and transient ischaemic attacks offers a further possibility of treatment.