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Research Article

Initial experience with indium-111 autologous leucocyte imaging in patients with acute pancreatitis.

Br Med J (Clin Res Ed) 1983; 287 doi: (Published 03 September 1983) Cite this as: Br Med J (Clin Res Ed) 1983;287:637
  1. J R Anderson,
  2. R A Spence,
  3. J D Laird,
  4. W R Ferguson,
  5. T L Kennedy


    Indium-111 labelled autologous leucocyte imaging was used to assess severity in 13 patients with acute pancreatitis. All three patients with severe disease as judged by a prognostic factor grading system had a positive result on imaging. A fourth patient with mild disease as judged by prognostic factors had a positive imaging result and 14 days later developed a pseudocyst. There were no false positive or false negative scans. Evidence from three patients suggested that a positive 111In-leucocyte imaging result implies substantial fat necrosis. In this study imaging was as accurate as prognostic factor grading. The technique may be a useful method of separating mild from severe acute pancreatitis.