Clinical Research

Hypoventilatory respiratory failure in generalised scleroderma

Br Med J (Clin Res Ed) 1983; 286 doi: (Published 29 January 1983) Cite this as: Br Med J (Clin Res Ed) 1983;286:337
  1. Gerald D Iliffe,
  2. Norman M Pettigrew


    A patient with generalised cutaneous and gastrointestinal scleroderma subsequently died from respiratory failure secondary to hyperventilation. At necropsy changes consistent with scleroderma of the diaphragm were found; these were thought to have contributed appreciably to the terminal respiratory failure.

    This case indicates that diaphragmatic changes should be added to the list of respiratory complications of scleroderma.

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