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Research Article

Disseminated malignant phaeochromocytoma: localisation with iodine-131-labelled meta-iodobenzylguanidine.

Br Med J (Clin Res Ed) 1982; 285 doi: (Published 23 October 1982) Cite this as: Br Med J (Clin Res Ed) 1982;285:1153
  1. H Sutton,
  2. P Wyeth,
  3. A P Allen,
  4. O A Thurtle,
  5. T K Hames,
  6. M I Cawley,
  7. D Ackery


    Meta-iodobenzylguanidine, a guanethidine analogue, is a newly synthesised substance capable of imaging the adrenal medulla. In a woman in whom phaeochromocytoma has been diagnosed iodine-131-labelled metaiodobenzylguanidine was given intravenously; gamma-camera images showed bilateral adrenal tumours and uptake corresponding to bone and liver metastases. 131I-meta-iodobenzylguanidine is effective in localising phaeochromocytomas, and the technique is safe, specific, and non-invasive.