Research Article

Objective test for food sensitivity in asthmatic children: increased bronchial reactivity after cola drinks.

Br Med J (Clin Res Ed) 1982; 284 doi: (Published 24 April 1982) Cite this as: Br Med J (Clin Res Ed) 1982;284:1226
  1. N Wilson,
  2. H Vickers,
  3. G Taylor,
  4. M silverman


    Ten asthmatic children with a history of cough and wheeze after drinking a cola drink performed histamine inhalation tests before and 30 minutes after a drink of Pepsi-Cola, soda water, and water on three separate study days. There was no significant change in baseline peak expiratory flow after any of the three drinks. Sensitivity to histamine was increased after the cola drink (p less than 0.005) but was not significantly different after soda water or water. The detection of change in sensitivity to histamine appears to be a simple and effective method of testing for food sensitivity in asthma.