Research Article
Plasmatic regulation of vascular prostacyclin in pregnancy.
Br Med J (Clin Res Ed) 1981; 282 doi: https://doi.org/10.1136/bmj.282.6263.512 (Published 14 February 1981) Cite this as: Br Med J (Clin Res Ed) 1981;282:512
- G Remuzzi,
- C Zoja,
- D Marchesi,
- A Schieppati,
- G Mecca,
- R Misiani,
- M B Donati,
- G de Gaetano
Abstract
Activity of prostacyclin-stimulating factor was measured in six normal, non-pregnant women, six women in early normal pregnancy, six in late normal pregnancy, and six in late pregnancy complicated by severe pre-eclampsia. The activity was lower in the women in late pregnancy than in those in early pregnancy and the controls but was about normal in those with severe pre-eclampsia. These results may be relevant to the physiology of pregnancy and the pathogenesis of pre-eclampsia.